Extended Reality

Extended reality (XR), which includes virtual reality, augmented reality, and spatial computing, is revolutionizing healthcare by providing immersive and interactive environments for medical research and clinical applications.
 
At the Duke Center for Computational and Digital Health Innovation, we use XR technologies to empower healthcare professionals to provide more personalized, precise, and effective healthcare solutions. XR allows our researchers to visualize and interact with complex 3D data in intuitive and immersive ways.

How We’re Using Extended Reality

By harnessing the power of XR, the Center for Computational and Digital Health Innovation is pushing the boundaries of precision, personalization, and collaboration in medicine.

Advancing Neurosurgical Precision

Neurosurgical procedures, particularly those involving deep brain stimulation (DBS), require highly accurate visualization and planning. At the Center, a team led by Prof. Cameron McIntyre has developed advanced holographic visualization techniques to reconstruct axonal pathways in the brain.

The method, known as Connectomic DBS, couples patient-specific DBS modeling with high-resolution MRI data. It provides clinicians with detailed insights, helping to improve the precision of electrode implantation in the brain. This technology is critical in treating neurological conditions like Parkinson’s disease and depression, enhancing the effectiveness of these interventions.

Enhancing Surgical Navigation with Augmented Reality

The use of AR in surgical settings is another groundbreaking application at our Center. Research led by Prof. Maria Gorlatova includes the development of Neurolens, an AR tool designed to track surgical instruments in real time during neurosurgery.

The tool overlays real-time imaging data onto the surgeon’s field of view, facilitating precise navigation and improving surgical outcomes. Beyond the operating room, our work in AR extends to applications in various industries, including gaming, retail, and education, demonstrating the versatility and potential of this technology in different contexts.

Making Cardiovascular Care More Intuitive

In the realm of cardiovascular care, XR technologies are being used to create highly detailed simulations of blood flow and disease progression. Prof. Amanda Randles and team have developed Harvis and HarVI, platforms that integrate VR and machine learning to facilitate detailed exploration and surgical planning.

HarVI enables simulation of post-intervention blood flow changes through AI, providing real-time feedback of interventions, while Harvis provides an intuitive Unity-based framework, allowing us to make use of all forms of XR for interacting with patient-specific anatomy. These tools allow for developing personalized treatment strategies and laying the groundwork to enable clinicians to better understand and manage cardiovascular conditions. We also have an arm of research completing user studies to formally assess when different aspects are needed to improve interaction.

Research Featuring Extended Reality

  • Example of Harvis visualization

    Harvis: Extended Reality Interface for Immersive Vascular Visualization

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  • Fluorescence microscopy image of a blood vessel aneurysm in red and green.

    Coupled Digital Twins as Surrogates to Assess Treatment of Cerebral Aneurysms

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  • HarVI AI-enabled, Real-time Extended Reality-Based Treatment Planning

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Publications Featuring Extended Reality

  • Workflow diagram of offline modeling and online planning for blood flow.

    Real-time virtual intervention for simple and serial coronary artery disease using the HarVI framework

    Virtual planning tools that provide intuitive user interaction and immediate hemodynamic feedback are crucial for cardiologists to effectively treat coronary artery disease. Current FDA-approved…

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  • A glowing pink figure on a blue background, abstract design.

    Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils

    Various types of embolization devices have been developed for the treatment of cerebral aneurysms. However, it is challenging to properly evaluate device performance and…

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  • Cover of Operative Neurosurgery

    Balloon-Mounted Stents for Treatment of Refractory Flow Diverting Device Wall Malapposition

    As indications for flow diversion (FD) have expanded, new challenges in deployment of flow diverting devices (FDDs) have been encountered. We present 4 cases…

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  • Cover of AIChE Journal

    Impact of diversity of morphological characteristics and Reynolds number on local hemodynamics in basilar aneurysms

    Morphological and hemodynamic parameters have been suggested to affect the rupture of cerebral aneurysms, but detailed mechanisms of rupture are poorly understood. The purpose…

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  • CT scan showing a cerebral aneurysm indicated by a red arrow.

    Hemodynamic and morphological characteristics of a growing cerebral aneurysm

    The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving mechanisms of the growth are poorly understood. The goal of…

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  • Rendering of arterial model

    The role of extended reality for planning coronary artery bypass graft surgery

    Immersive visual displays are becoming more common in the diagnostic imaging and pre-procedural planning of complex cardiology revascularization surgeries. One such procedure is coronary…

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  • Cover of Computational Science journal

    Harvis: an interactive virtual reality tool for hemodynamic modification and simulation

    Cardiovascular disease (CVD) affects more than 90 million adults in the United States. In recent years, computational hemodynamic models have helped improve our understanding of CVD…

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  • Cover of Computational Science journal

    HarVI: Real-Time Intervention Planning for Coronary Artery Disease Using Machine Learning

    Virtual planning tools that provide intuitive user interaction and immediate hemodynamic feedback are crucial for cardiologists to effectively treat coronary artery disease. Current FDA-approved…

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