Cancer

T cells examples

Establishing a massively parallel computational model of the adaptive immune response

Parallel agent-based models of the adaptive immune response can efficiently recapitulate emerging spatiotemporal properties of T-cell motility during clonal selection across multiple length and time scales. Here, we present a distributed, three-dimensional (3D) computational model of T-cell priming, and associated parallel data structures and algorithms that enable fully deterministic cell simulations at scale. We demonstrate…

Blood vessels

Research team pairs 3D bioprinting and computer modeling to examine cancer spread in blood vessels

Researchers at Lawrence Livermore National Laboratory and Duke University combined 3D bioprinting and computational flow models to analyze the physics behind circulating tumor cell behavior and the cells’ attachment to the vascular endothelium, the layer of cells that line the interior surface of blood vessels.