Cardiology

The advent of digital twins has increased the demand for longer-duration simulations that span multiple physiological states. Digital twins have emerged as powerful tools in cardiovascular modeling, enabling patient-specific simulations of coronary blood flow for noninvasive diagnosis and treatment planning. Although these simulations achieve high fidelity under steady or periodic heart rates, modeling real-world transitions,…

Aortic coarctation (CoA) comprises 6%–8% of all congenital heart diseases and is the second most common cardiovascular disease requiring neonatal surgical correction. However, patients remain at high risk for long-term complications, notably recoarctation. Methods: Hemodynamic simulations were performed in a group of six patients following CoA repair, as compared to a group of age and sex-matched…