Extended Reality

Workflow diagram of offline modeling and online planning for blood flow.

Real-time virtual intervention for simple and serial coronary artery disease using the HarVI framework

Virtual planning tools that provide intuitive user interaction and immediate hemodynamic feedback are crucial for cardiologists to effectively treat coronary artery disease. Current FDA-approved tools for coronary intervention planning require days of preliminary processing and rely on conventional 2D displays for hemodynamic evaluation. Immersion offered by extended reality (XR) has been found to benefit intervention…

A glowing pink figure on a blue background, abstract design.

Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils

Various types of embolization devices have been developed for the treatment of cerebral aneurysms. However, it is challenging to properly evaluate device performance and train medical personnel for device deployment without the aid of functionally relevant models. Current in vitro aneurysm models suffer from a lack of key functional and morphological features of brain vasculature that limit…

Cover of Operative Neurosurgery

Balloon-Mounted Stents for Treatment of Refractory Flow Diverting Device Wall Malapposition

As indications for flow diversion (FD) have expanded, new challenges in deployment of flow diverting devices (FDDs) have been encountered. We present 4 cases with aneurysms in which deployment of FDDs were complicated by device malapposition and compromised opening in regions of parent vessel stenosis. In all 4 cases, a balloon-mounted stent was ultimately deployed…

Cover of AIChE Journal

Impact of diversity of morphological characteristics and Reynolds number on local hemodynamics in basilar aneurysms

Morphological and hemodynamic parameters have been suggested to affect the rupture of cerebral aneurysms, but detailed mechanisms of rupture are poorly understood. The purpose of our study is to determine criteria for predicting the risk of aneurysm rupture, which is critical for improved patient management. Existing aneurysm hemodynamics studies generally evaluate limited geometries or Reynolds…

CT scan showing a cerebral aneurysm indicated by a red arrow.

Hemodynamic and morphological characteristics of a growing cerebral aneurysm

The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving mechanisms of the growth are poorly understood. The goal of this study was to examine the association between intraaneurysmal hemodynamic features and areas of aneurysm growth, to present the key hemodynamic parameters essential for an accurate prediction of the growth, and…

Rendering of arterial model

The role of extended reality for planning coronary artery bypass graft surgery

Immersive visual displays are becoming more common in the diagnostic imaging and pre-procedural planning of complex cardiology revascularization surgeries. One such procedure is coronary artery bypass grafting (CABG) surgery, which is a gold standard treat-ment for patients with advanced coronary heart disease. Treatment planning of the CABG surgery can be aided by extended reality (XR)…