2020

A glowing pink figure on a blue background, abstract design.

Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils

Various types of embolization devices have been developed for the treatment of cerebral aneurysms. However, it is challenging to properly evaluate device performance and train medical personnel for device deployment without the aid of functionally relevant models. Current in vitro aneurysm models suffer from a lack of key functional and morphological features of brain vasculature that limit…

Cover of Operative Neurosurgery

Balloon-Mounted Stents for Treatment of Refractory Flow Diverting Device Wall Malapposition

As indications for flow diversion (FD) have expanded, new challenges in deployment of flow diverting devices (FDDs) have been encountered. We present 4 cases with aneurysms in which deployment of FDDs were complicated by device malapposition and compromised opening in regions of parent vessel stenosis. In all 4 cases, a balloon-mounted stent was ultimately deployed…

Cover of Computational Science journal

Harvis: an interactive virtual reality tool for hemodynamic modification and simulation

Cardiovascular disease (CVD) affects more than 90 million adults in the United States. In recent years, computational hemodynamic models have helped improve our understanding of CVD progression; however, such research workflows can be challenging and unintuitive to operate. We thus developed Harvis, a software platform with a flexible GUI for performing vascular simulations and a VR-capable interface…