In healthcare, the emergence of digital twin technology marks a transformative step towards proactive medical care. Digital twins, which are detailed virtual models of individual human physiological systems, are reshaping how medical professionals predict, diagnose, and treat various health conditions. In her talk, Amanda Randles discusses how the specific application of these models can create personalized simulations of the vascular system. These simulations allow for the precise analysis of blood flow and the noninvasive assessment of vascular diseases such as stenosis, offering a significant leap in both diagnostics and pre-surgical planning.