2019

CT scan showing a cerebral aneurysm indicated by a red arrow.

Hemodynamic and morphological characteristics of a growing cerebral aneurysm

The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving mechanisms of the growth are poorly understood. The goal of this study was to examine the association between intraaneurysmal hemodynamic features and areas of aneurysm growth, to present the key hemodynamic parameters essential for an accurate prediction of the growth, and…

Person using VR headset to interact with information

Investigating the Role of VR in a Simulation-Based Medical Planning System for Coronary Interventions

Virtual reality (VR) based computational fluid dynamics (CFD) simulations are emerging as a viable solution to guide complex surgical or invasive procedures, such as percutaneous coronary intervention (PCI), as they enable a realistic first-person experience of underlying patient anatomy and physiology. Realistic VR experience can be assessed by immersion, an objective VR property. However, it…

Heatmap showing coronary artery branch importance in 3D hemodynamic modeling.

The importance of side branches in modeling 3D hemodynamics from angiograms for patients with coronary artery disease

Genesis of atherosclerotic lesions in the human arterial system is critically influenced by the fluid mechanics. Applying computational fluid dynamic tools based on accurate coronary physiology derived from conventional biplane angiogram data may be useful in guiding percutaneous coronary interventions. The primary objective of this study is to build and validate a computational framework for…